Fig. 2
From: Microglial dynamics after axotomy-induced retinal ganglion cell death
RGC clearance and PMC appearance in axotomized retinas. Magnifications from flat-mounted traced retinas analyzed at 2 (a, b), 5 (c, d), 9 (e, f), 14 days (g, h), or 2 months (i, j) after optic nerve crush (first column) or transection (second column) showing the course of FG+RGC disappearance and the appearance of PMCs (yellow arrows). k–n Images from the central dorso-temporal area (drawing in k, top right) of a representative retina analyzed 14 days after ONT and immunodetected with Iba1 and Brn3a. PMCs are those MCs transcellularly labeled (FG+Iba+). In these injured retinas, majority of FG−Iba+ MCs are probably activated, but have not yet engulfed a traced RGC