Fig. 1
From: EZH2 suppression in glioblastoma shifts microglia toward M1 phenotype in tumor microenvironment
EZH2 inhibition induces mRNAs changes of inflammatory cytokines in GBM cells. a and b Human U87 cells were treated with siEZH2 and DZNep for 24 h, and then, mRNA levels of several cytokines were determined by quantitative real-time PCR. c and d Human U251 cells were treated similar to U87, and mRNA expression of several cytokines were determined by qPCR. e and f Murine GL261 cells were treated similar to U87, and mRNA expression of several cytokines were determined by real time PCR. NC and PBS were set as controls, respectively, and nothing were added to mock group. All these experiments were repeated thrice. *p < 0.05, compared with corresponding control group