Fig. 3

NAIVE-AS, EAE-AS, and anti-MOG binding on BrdU⁺ cells in normal mouse brain in three age groups. a–c SVZ sections of neonates, e–g postnates, and i, j, k adults double-stained with anti-BrdU and NAIVE-AS, EAE-AS, and anti-MOG, respectively. Arrows denote the double positive cells for BrdU⁺/EAE-AS⁺ and BrdU⁺/anti-MOG⁺. Scale bars=200 μm. d–l Graphs represent the corresponding anti-BrdU co-expression % with NAIVE-AS, EAE-AS, and anti-MOG. BrdU⁺/EAE-AS⁺ cell populations are widespread in three age groups versus BrdU⁺/anti-MOG⁺, especially in postnates (* p < 0.05, ** p < 0.01, *** p < 0.001)