Fig. 1
From: Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome
XCT expression in wild-type (WT) versus Mecp2-null mice. a At 1 week of age, XCT mRNA expression was increased in Mecp2-null mice. b XCT mRNA expression increased significantly after stimulation with lipopolysaccharide toxin (LPS; checkered bars) in primary mixed glial cultures from WT and Mecp2-null mice. The response to LPS was also significantly increased in Mecp2-null compared to WT primary mixed glial cells. Mean values ± SEM for graphs in a and b (#p = 0.06; *p < 0.05; ***p < 0.001)