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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome

Fig. 4

Effects of LPS stimulation on XCT and TNF-α expression. a XCT expression in BV2 cells was increased after LPS stimulation (*p < 0.05). b BV2 cell cultures treated with D-NAC showed dose-dependent decreases in TNF-α concentration in the supernatant as compared to LPS-treated (activated) cultures. Only the highest dose of NAC (100 μg/mL) was effective at reducing TNF-α concentration

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