Table 1 Demographic and clinical characteristics of multiple sclerosis patients and controls included in the CSF experiments

Cohort

N

Gender (male/female)

Mean age ± SD in years

1

24

 RRMS

7

2/5

40.4 ± 8.9

 SPMS

5

1/4

47.8 ± 5.6

 PPMS

4

3/1

47.0 ± 9.2

 NHI

8

3/5

40.0 ± 6.1

2

115

 CIS

12

3/9

37.9 ± 9.4

 RRMS

15

3/12

41.6 ± 5.0

 SPMS

12

4/8

49.1 ± 9.2

 PPMS

11

4/7

49.9 ± 11.9

 NHI

34

12/22

53.8 ± 14.8

 IND

4

0/4

50.2 ± 16.8

 AD

17

8/9

70.4 ± 9.1

 IIH

10

1/9

31.4 ± 6.7

Cohort

N

Gender (male/female)

Median age (interquartile range) in years

EDSS

Interferon-beta used (%)

3

112

 RRMS

44

18/26

40.6 (34.6–49.9)

3.0 (2.5–4.0)

36.4

 SPMS

33

19/14

48.1 (43.9–53.8)

6.0 (4.0–6.8)

36.4

 PPMS

13

8/5

52.2 (47.6–56.3)

4.0 (3.8–6.3)

0

 IND

6

4/2

37.8 (23.1–60.1)

2.5^a

0

 NIND

16

10/6

43.2 (31.3–54.1)

1.0^a

0