Skip to main content
Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress

Fig. 6

Chronic DMXBA treatment prevents chronic restraint stress (CRS)-induced cholinergic insufficiency. a Relative levels of α7nAChR protein in hippocampus. Results are shown as fold change relative to GAPDH protein level. b Representative immunoblots and relative levels of choline acetyltransferase (ChAT) protein in hippocampus. Results are shown as fold change relative to GAPDH protein level. c Acetylcholinesterase (AChE) activity in hippocampus of different groups. d Representative immunoblots and relative levels of STAT3 protein in hippocampus. Data are shown as fold change relative to histone protein level. Con, control group. Data are presented as mean ± SEM. n = 8 per group; *P < 0.05 vs. control group; # P < 0.05 vs. CRS 21d + Veh group

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094