Fig. 4

Scrambled Aβ does not change the mRNA levels for selected cytokines and iNOS in the hippocampus. Aβ (0.5 nmol) or Aβ scrambled (Aβscr, 0.5 nmol) were injected intracerebroventricularly and gene expression was analysed 3 h after injection by quantitative RT-PCR. The results were normalised to β-actin gene expression and are presented as the mean ± SEM from 6 to 12 independent experiments (n = 6–12). *, ***p < 0.05 and 0.001 compared with the respective control; ^#, ^##, ^###p < 0.05, 0.01 and 0.001 compared with the Aβ_1–42-treated animals using nonparametric Kruskal-Wallis followed by Dunn’s multiple comparisons test