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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Reciprocal interactions between prostaglandin E2- and estradiol-dependent signaling pathways in the injured zebra finch brain

Fig. 2

Central levels of prostaglandin E2 (PGE2) in sham animals or following bilateral injury with prostanoid receptor antagonism in adult male and female zebra finches (A and B). Treatment with EP-3 or EP-4 antagonist during brain injury does not affect the induction of PGE2 (A and B) compared to sham controls. However, receptor antagonism decreases downstream signaling (PKA) compared to control-injured brains (C). Dashed line represents injured controls (controls set to 1 for fold change calculation). *p < 0.05

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