BCS | MS | p value | |
---|---|---|---|
Number of patients | 132 | 267 [17] | n.a. |
Number of samples | 146 | 267 [17] | n.a. |
Sex ratio (male to female) | 1:1.54 | 1:1.95 [17] | n.s. |
Median age at first lumbar puncture (range) | 32 years (4–60) | 36 years [17] | n.d. |
Relapsing disease course | 27/102 (26.5%) | n.d. [17] | n.d. |
CSF-restricted OCB, positive, samples | 34.1% (29/85) | 98.1% (262/267) [17] | < 0.000001 |
CSF-restricted OCB, positive, patients | 35% (28/80) | 98.1% (262/267) [17] | < 0.000001 |
CSF-restricted OCB, transiently positive, patients | 50% (1/2) | n.d. | n.a. |
Link’s IgG index, elevated, samples | 22.6% (7/31) | 86.4% (51/59) [20] | < 0.000001 |
Link’s IgG index, elevated, patients | 25% (7/28) | 86.4% (51/59) [20] | < 0.000001 |
CSF WCC, elevated, samples | 28.1% (27/96) | 58.4% (156/267) [17] | < 0.000001 |
CSF WCC, median and range, if increased, samples | 27/μl (6–371) | < 40/μl in 98% [17] | n.a. |
CSF TP, elevated, samples | 40.8% (31/76) | n.d. | n.a. |
CSF TP, median and range, if increased, samples | 75 (46–280) | n.d. | n.a. |
ACD, samples | 23.6% (17/72) | 1.9% (1/54) | < 0.0005 |