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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Porphyromonas gingivalis lipopolysaccharide induces cognitive dysfunction, mediated by neuronal inflammation via activation of the TLR4 signaling pathway in C57BL/6 mice

Fig. 3

Effects of P.gingivalis-LPS on spatial learning of mice during the Morris water maze (MWM) test. Effects of treatment with P.gingivalis-LPS (5 mg kg−1, i.p.) alone or in combination with TAK-242 (5 mg kg−1, i.p.) on latency to find the platform during the acquisition phase of the MWM test. Data are presented as mean ± SEM; *p < 0.05, **p < 0.01 and ***p < 0.001, compared to the control group; #p < 0.05 and ##p < 0.01, compared to the P.gingivalis-LPS group

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