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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation

Fig. 7

Overview of the effect of episodic systemic inflammation and aging on microglia. Young microglia have highly branched processes and are responsive to stimuli, contributing to tissue homeostasis. Aged microglia are dystrophic and resistant to regulation. Episodic systemic inflammation contributed to age-related microglia phenotype that was associated with age-related cognitive impairments

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