Fig. 5
From: Ablation of caspase-1 protects against TBI-induced pyroptosis in vitro and in vivo
Neuron injury-induced apoptosis in cultured primary neuron. a Flow cytometer results for apoptosis following scratch-, stretch-, and LPS/ATP-induced neuron damage. Scratch, stretch, and LPS/ATP stimulation induced significant apoptosis in cultured primary neuron (***p < 0.001, relative to the normal group). b Culture supernatant was collected to detect LDH release by scratch, stretch, and LPS/ATP stimulation. Supernatant LDH concentration increased by scratch, stretch, and LPS/ATP stimulation (p < 0.001). All data are expressed as means ± SEM; one representative experiment of five was shown