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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Intraocular DHODH-inhibitor PP-001 suppresses relapsing experimental uveitis and cytokine production of human lymphocytes, but not of RPE cells

Fig. 4

Cytokine secretion of PHA-stimulated human PBL treated with PP-001. Cytokine secretion of PHA-stimulated human PBL from four donors with or without PP-001 (3 and 30 μM, respectively). Supernatants from triplicate cultures were collected at three time points (24, 48, and 72 h after onset of cultures, in total nine samples) and pooled for the final bioplex analysis. Cytokine secretion of cultures with PHA only is defined as 100%; the percentage of secretion in cultures with PP-001 is respectively calculated in relation to the PHA-control for each donor. Data show the means of % secretion from four different donors + SE, p values are only shown for significantly different data

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