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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor

Fig. 3

GPNMB reduces inflammatory mediators in cultured astrocytes. a–b Gene expression of the inflammatory factors IL-6 (a) and gp91phox (b) in IMA cells (left panel) and PMAs (right panel). c H2DCF-DA fluorescence intensity measuring intracellular ROS generation in IMA (left panel) and PMA (right panel) cells. Asterisks denote statistically significant differences between the different treatment groups or compared to the control (*p < 0.05, **p < 0.01, and ***p < 0.001)

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