Fig. 3
HO-1 (GT)n repeat length does not correlate with plasma or CNS viral load or blood CD4 T-cell count in HIV-infected individuals. Correlations between an HIV+ individual’s shortest (GT)n allele length and a plasma viral load (HIV copies/ml), b CSF viral load (HIV copies/ml), c brain parenchyma viral load (HIV copies/g), and d peripheral blood CD4 T-lymphocyte count (cells/mm3). Solid lines represent best-fit linear regression models with dashed lines showing 95% confidence bands. Statistical analysis was performed by Spearman rank correlation. e Plasma viral load, f CSF viral load, g brain parenchyma viral load, and h peripheral blood CD4 T-lymphocyte count in HIV+ individuals with a short ‘S’ allele (SS, SM, SL) and those without a short ‘S’ allele (MM, ML, LL). Lines and error bars indicate median ± 95% confidence interval. All viral load data is log10 transformed. Differences between groups were analyzed by Mann-Whitney test. n.s., not significant