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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Heme oxygenase-1 promoter region (GT)n polymorphism associates with increased neuroimmune activation and risk for encephalitis in HIV infection

Fig. 5

Length of the shortest HO-1 (GT)n allele correlates positively with CNS expression of markers of type I interferon responses and T-lymphocyte activation in HIV-infected individuals. Correlations were determined between the length of an HIV-infected (without HIVE) individuals shortest HO-1 (GT)n allele and the prefrontal cortex expression of the RNA markers a MX1, b ISG15, c IRF1, d CD38, e GZMB, f CD8A, g CD68, h CD163, i CD19, j PECAM1, and k VWF. Significant associations were determined by Spearman rank correlation. Solid lines represent best-fit linear regression models with dashed lines showing 95% confidence bands. Red regression lines denote significant differences. r, Spearman rank coefficient; n.s., not significant

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Journal of Neuroinflammation

ISSN: 1742-2094