Fig. 5

Dexamethasone modulates S100B levels in the hippocampus and in the cerebrospinal fluid. S100B content was measured by ELISA. Dexamethasone prevented the augmentation in S100B content in the hippocampus of SE animals at 1 day after treatment (a) and did not affect S100B content at 56 days after SE induction (b). The augmentation in S100B levels in the CSF was prevented by dexamethasone at 56 days after SE induction (d). Serum S100B levels were not altered by dexamethasone at any of the time points (e, f). Values represent mean ± standard error, of four to six animals per group. Data were analyzed by ANOVA, followed by the Tukey test. Bars without a common letter differ significantly, assuming p < 0.05