Fig. 3
From: Therapeutic time window of multipotent adult progenitor therapy after traumatic brain injury
Multipotent adult progenitor cell treatment reduced the number of activated microglia/macrophages in the ipsilateral dentate gyrus. Traumatic brain injury resulted in chronic activation of microglia/macrophages that was attenuated with MAPC treatment at 2/24 h after injury in the dentate gyrus. a–c Photomicrographs of microglia/macrophages from sham (a), CCI (b), and CCI-2/24 (c) animals using IBA1 antibody (white). Scale bars 1000 μm (× 1.25), 100 μm (× 20); inset 25 μm. d Number of inactivated and activated microglia/macrophages in the dentate gyrus of the ipsilateral hippocampus at 2/24 h