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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Central blockade of NLRP3 reduces blood pressure via regulating inflammation microenvironment and neurohormonal excitation in salt-induced prehypertensive rats

Fig. 8

Central blockade NLRP3 suppresses of VCAM-1, CXCR3, and CCL2 expression in the PVN of prehypertensive rats. a A representative immunoblot of VCAM-1, CXCR3, and CCL2. b Densitometric expression analysis of VCAM-1, CXCR3, and CCL2 in various groups, n = 3. c Terminated treatment of anti-NLRP3, a representative immunoblot of VCAM-1, CXCR3, and CCL2. d Densitometric protein analysis of VCAM-1, CXCR3, and CCL2 in various groups; n = 3. e ELISA detection IL-6 expression in the PVN of the various groups, n = 6–8. f ELISA detection TNF-α expression in the PVN, n = 6–8. Values are expressed as means ± SEM. *P < 0.05, **P < 0.001. ***P < 0.0001

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