Fig. 6

The cerebrospinal fluid concentration indexes of CXCL1, CXCL2, and Th17 cytokines

The indexes of the cerebrospinal fluid (CSF) concentrations of chemokines CXCL1 and CXCL2 and interleukins IL-17A, IL-17F, and IL-22 in 14 TBE patients in the neurologic phase of the infection, calculated as described in the “Methods” section. Shown are values in individual patients (blue symbols) and median (black horizontal line), patients with meningoencephalitis are highlighted with circles and patients with meningitis with dots. The additional values obtained in 3 patients before the peak neurologic phase of TBE are shown to the left of each cytokine plot by colored points: red—patients 1 and 2 examined in the peripheral phase and orange—patient 4 examined early in the neurologic phase, before the maximum pleocytosis. Individual data points for some cytokines are missing because of the undetectable serum and/or CSF cytokine levels. **The significant difference between the meningitis and meningoencephalitis patients (p < 0.01).