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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in mice

Fig. 5

MC4R antagonist and AMPK inhibitor reversed the effects of RO27-3225 on neurobehavioral outcomes after ICH. a Modified Garcia test, b forelimb placement test, c corner turn test, and d the effects of RO27-3225 on body weight loss at 24 h after ICH. *p < 0.05 vs. sham, #p < 0.05 vs. ICH + vehicle, @p < 0.05 vs. ICH + RO27-3225 + HS024, and &p < 0.05 vs. ICH + RO27-3225 + DMSO. Error bars are represented as mean ± SD. One-way ANOVA, Tukey’s test, n = 6 per group

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Journal of Neuroinflammation

ISSN: 1742-2094