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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in mice

Fig. 7

The effects of RO27-3225 and AMPK inhibitor dorsomorphin on the expression of MC4R and its downstream signaling proteins. a Representative western blot bands. bg Quantitative analyses of MC4R, phosphorylated AMPK, phosphorylated JNK, phosphorylated p38 MAPK, TNF-α, and IL-1β in the ipsilateral hemisphere at 24 h after ICH. *p < 0.05 vs. sham, #p < 0.05 vs. ICH + vehicle, and &p < 0.05 vs. ICH + RO27-3225 + DMSO. Error bars are represented as mean ± SD. One-way ANOVA, Tukey’s test, n = 6 per group

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