Fig. 3
From: Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice
MSCs reversed gap formation of ZO-1, occludin, and claudin-5. Sections from ischemic penumbra were stained of ZO-1, occludin, and claudin-5 (red) and then co-stained with endothelial marker CD31 (green). Discontinuous labeling and gap formation (white arrows) were observed in ipsilateral brains following 3 days of tMCAO. Scale bar = 30 μm. Data are mean ± SD, n = 5–6 per group. *p < 0.05, **p < 0.01, ***p < 0.001