Fig. 4
From: Neuroinflammation is increased in the parietal cortex of atypical Alzheimer’s disease
CD68 and HLA-DP/DQ/DR immunoreactivity show a parietal dominant distribution in atypical AD. a, b In typical AD, the temporal section (blue border) shows more CD68 and HLA-DP/DQ/DR immunoreactivity than the parietal section (burgundy border). In contrast, atypical AD shows more CD68 and HLA-DP/DQ/DR immunoreactivity in the parietal than the temporal section. Note the relative difference in immunoreactivity in the parietal section of atypical AD compared to the temporal section in typical AD. Bar represents 100 μm. c, d Boxplot showing CD68 and HLA-DP/DQ/DR immunoreactive area (%) in the temporal and parietal section, respectively, of both AD phenotypes. Linear mixed model shows a different distribution over the 2 regions between phenotypes (#) (Table 5). *p < .0045