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Table 1 Demographics of 36 cases with typical and atypical NFT distribution for which extensive retrospective clinical assessment was performed

From: Neuroinflammation is increased in the parietal cortex of atypical Alzheimer’s disease

  Typical NFT distribution
n = 18
Atypical NFT distribution
n = 18
Phenotype Amnestic (n = 16) Non-amnestic (n = 2) Amnestic (n = 5) Non-amnestic (n = 13)
Male, n (%) 6 (37) 0 3 (60) 8 (62)
Age at death 82 (± 7) 88 (± 5) 71 (± 11) 67(± 7)
Disease duration 8 (± 5) 7 (± 4) 11 (± 5) 8 (± 4)
NFT stage [7]
n per stage 4/5/6 2/10/4 1/1/0 0/2/3 0/7/6
Amyloid stage [7]
n per stage O/A/B/C 0/0/16 0/0/2 0/0/5 0/1/12
  1. Data are mean ± SD. Age at death and disease duration shown in years
  2. NFT neurofibrillary tangle