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Table 1 Demographics of 36 cases with typical and atypical NFT distribution for which extensive retrospective clinical assessment was performed

From: Neuroinflammation is increased in the parietal cortex of atypical Alzheimer’s disease

 

Typical NFT distribution

n = 18

Atypical NFT distribution

n = 18

Phenotype

Amnestic (n = 16)

Non-amnestic (n = 2)

Amnestic (n = 5)

Non-amnestic (n = 13)

Male, n (%)

6 (37)

0

3 (60)

8 (62)

Age at death

82 (± 7)

88 (± 5)

71 (± 11)

67(± 7)

Disease duration

8 (± 5)

7 (± 4)

11 (± 5)

8 (± 4)

NFT stage [7]

n per stage 4/5/6

2/10/4

1/1/0

0/2/3

0/7/6

Amyloid stage [7]

n per stage O/A/B/C

0/0/16

0/0/2

0/0/5

0/1/12

  1. Data are mean ± SD. Age at death and disease duration shown in years
  2. NFT neurofibrillary tangle