Coro1a
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Coronin1a
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Cell membrane associated protein that interacts with actin filaments to facilitate cell motility, endocytosis, and phagocytosis. Loss of Coro1a expression or ability to bind to F-actin impairs these processes [53].
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ATP6ap1
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ATPase H+ transporting accessory protein 1
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Component of the H+ transporting vacuolar ATPase present in phagosomes [54]
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Fcgr1a
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Fc fragment of IgG receptor Ia
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Complexes with leukotriene B4 receptor in lipid rafts, enhances macrophage anti-microblial actions [55]
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RT1
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Proteins of the MHC class I family, involved in antigen presentation.
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Ctss
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Cathepsin S
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Peptidase present in phagolysosomes where it degrades various target proteins [56]
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Cyba
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Cytochrome b-245 alpha chain
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Ncf1
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Neutrophil cytosolic factor 1
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Components of the NADPH Oxidase complex, present in phagolysomes.
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Slc11a1
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Solute carrier family 11 member a1, also referred to as Nramp1
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Transmembrane phagosomal divalent cation transporter [57]
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Mfge8
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Ligand milk fat globule EGF factor-8
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Ligand for Itgb5 (integrain subunit beta 5) required for activation of several pathways, including MerTK activation and F-actin recruitment, involved in clearance [58]
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Psap
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Prosaponin
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Precursor of saposins A, B, C, and D, which have roles in lysomal degradation pathways [59]
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Sirpa
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Signal regulatory protein alpha
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Macrophage receptor for CD47 which is a broad inhibitor of phagocytosis [60, 61]
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Calr
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Calreticulin
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When present on the cell surface acts as a signal to activate macrophage phagocytosis [62]
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CD300lf
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Member of the CD300 receptor family
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Roles in activating macrophage engulfment by phosphatidylserine signaling [63]
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Pycard
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PYD And CARD Domain Containing, also referred to as ASC (Apoptosis-Associated Speck-Like)
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Component of the NLRP3 inflammasome, recently shown to play a role in amyloid deposition. [64]
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