Fig. 4

Decrease in splenic CD49d⁺ monocytes and decline in brain monocyte infiltration in TAK1^ΔM mice after stroke. a Decrease in the frequency of CD49d⁺splenic monocytes. b Decrease in the CD49d MFI on splenic monocytes. c Decrease in frequency of CD49d⁺ monocyte in the brain of TAK1^ΔM MCAo mice. d Increase in the frequency of splenic CD49d⁺ neutrophils. e No difference in the frequency of brain CD49d⁺ neutrophils after MCAo. f Representative flow plots showing CD49d gating on monocytes. Data is presented as mean ± SEM, n = 3–5; *p < 0.05, **p < 0.01, ***p < 0.001 (two-way ANOVA followed by post-hoc Tukey)