Sinomenine exerts anticonvulsant profile and neuroprotective activity in pentylenetetrazole kindled rats: involvement of inhibition of NLRP1 inflammasome

Table 1 Experimental group for performing SN’s anticonvulsant and neuroprotective effects. PTZ was administered to rats every other day. Saline and SN were administered to rats at 30 min prior to PTZ once every day

Experimental group	Saline	PTZ	SN
Control	Yes	No	No
SN	No	No	80 mg/kg
PTZ	No	35 mg/kg	No
PTZ + SN	No	35 mg/kg	20 mg/kg
	No	35 mg/kg	40 mg/kg
	No	35 mg/kg	80 mg/kg

ISSN: 1742-2094