Skip to main content

Table 2 Experimental group for performing SN washout. PTZ was administered to rats every other day. Saline and SN were administered to rats at 30 min prior to PTZ once every day. Rats in SNW (SN washout) group was only received PTZ after 14 PTZ injections

From: Sinomenine exerts anticonvulsant profile and neuroprotective activity in pentylenetetrazole kindled rats: involvement of inhibition of NLRP1 inflammasome

Experimental group

Number of PTZ injection

(1–14)

Number of PTZ injection

(15–19)

Saline

PTZ

SN

Saline

PTZ

SN

Control

Yes

No

No

Yes

No

No

PTZ

No

35 mg/kg

No

No

35 mg/kg

No

PTZ + SN

No

35 mg/kg

40 mg/kg

No

35 mg/kg

40 mg/kg

SNW

No

35 mg/kg

40 mg/kg

No

35 mg/kg

No