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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Vitexin reduces epilepsy after hypoxic ischemia in the neonatal brain via inhibition of NKCC1

Fig. 6

Vitexin suppressed spontaneous EEG seizures following hypoxia-induced neonatal seizures in vivo. a Representative traces of electroencephalograph (EEG) recordings from the sham (top, black trace), HI (middle, red trace), and HI+Vit (bottom, blue trace) groups. b The histograms demonstrate the seizure intensity stage of the sham, HI, and vitexin-treated groups incited after 40 mg/kg PTZ treatment. Vitexin treatment after HI showed a strong tendency to decrease the mean duration and frequency of seizure events in rats after hypoxia-induced seizures in 2-h recording sessions (c, d). n = 8~ 11 rats per experimental group. **P < 0.01, ***P < 0.001; one-way ANOVA with the Newman-Keuls test

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