Fig. 6
From: Vitexin reduces epilepsy after hypoxic ischemia in the neonatal brain via inhibition of NKCC1
Vitexin suppressed spontaneous EEG seizures following hypoxia-induced neonatal seizures in vivo. a Representative traces of electroencephalograph (EEG) recordings from the sham (top, black trace), HI (middle, red trace), and HI+Vit (bottom, blue trace) groups. b The histograms demonstrate the seizure intensity stage of the sham, HI, and vitexin-treated groups incited after 40 mg/kg PTZ treatment. Vitexin treatment after HI showed a strong tendency to decrease the mean duration and frequency of seizure events in rats after hypoxia-induced seizures in 2-h recording sessions (c, d). n = 8~ 11 rats per experimental group. **P < 0.01, ***P < 0.001; one-way ANOVA with the Newman-Keuls test