Fig. 8
From: Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening
Expression of proinflammatory cytokines in organotypic slices control (CTL) and with spontaneous epileptiform activity (EL) at 14 DIV. a RT-qPCR analysis of IL-1β, TNF-α, and IL-6 shows a transcript upregulation for all cytokines in EL slices. b IL-1β and IL-6 protein concentration in tissue, assessed by ELISA, is also significantly increased in EL slices. All values are mean ± SEM. n = 3–4, *p < 0.05, unpaired t test