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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening

Fig. 8

Expression of proinflammatory cytokines in organotypic slices control (CTL) and with spontaneous epileptiform activity (EL) at 14 DIV. a RT-qPCR analysis of IL-1β, TNF-α, and IL-6 shows a transcript upregulation for all cytokines in EL slices. b IL-1β and IL-6 protein concentration in tissue, assessed by ELISA, is also significantly increased in EL slices. All values are mean ± SEM. n = 3–4, *p < 0.05, unpaired t test

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