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Table 1 Laboratory characteristics of animals before and after treatment modification

From: Brain 18F-FDG PET of SIV-infected macaques after treatment interruption or initiation

  Interruption Initiation
Baseline Month 1 Month 3 Month 6 Baseline Month 1 Month 3 Month 6
CSF VL 0 (0) 272 (409) 16,741 (29,877) 327 (462) 6894 (10,533) 0 (0) 212 (473) 0 (0)
Log CSF VL 0 (0) 1.32 (1.54) 2.41 (2.29) 1.41 (1.99) 2.46 (2.56) 0 (0) 0.60 (1.35) 0 (0)
Plasma VL 3 (5) 79,070 (145,887) 258,608 (303,812) 919,845 (1,300,023) 362,834 (449,170) 41 (67) 20 (33) 8 (8)
Log plasma VL 0.27 (0.45) 4.11 (0.99) 4.10 (2.11) 4.52 (2.47) 4.89 (1.15) 1.15 (0.79) 0.79 (0.80) 0.65 (0.60)
CD4+ cells 783 (363) 576 (295) 450 (345) 526 (343) 235 (85) 487 (331) 444 (107) 648 (135)
Proliferating CD4+ cells 42 (22) 26 (7) 24 (16) 15 (13) 12 (5) 25 (9) 29 (16) 43 (17)
CD8+ cells 807 (424) 726 (385) 710 (427) 636 (350) 424 (256) 763 (483) 585 (415) 664 (258)
Proliferating CD8+ cells 29 (19) 36 (21) 61 (63) 38 (7) 24 (13) 35 (22) 28 (14) 40 (21)
CD4/CD8 ratio 0.98 (0.16) 0.83 (0.20) 0.67 (0.24) 0.80 (0.10) 0.64 (0.20) 0.70 (0.21) 0.93 (0.38) 1.08 (0.35)
  1. Data are shown as mean values with standard deviations in parentheses