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Table 1 Demographic data and classic CSF biomarker levels

From: Levels of ADAM10 are reduced in Alzheimer’s disease CSF

Group

Age (years)

n (gender)

CSF Aβ42 (pg/mL)

CSF T-tau (pg/mL)

CSF P-tau (pg/mL)

NADC

70 ± 2 [55–88]

n = 26 (8F/18M)

773 ± 29 [1010–561]

238 ± 13 [138–365]

36 ± 2 [21–51]

AD

71 ± 1 [55–86]

n = 27 (20F/7M)

414 ± 15* [544–251]

689 ± 48* [1420–443]

88 ± 5* [164–61]

  1. Patients were designated as NADC or AD according to CSF biomarker levels using cutoffs as described in the “Methods” section (and ref. [27]). The data represent the means ± SEM. The ranges of values for each variable are also indicated. F female; M male. *Significantly different (p < 0.001) from the NADC group