Fig. 2

Compound 21 had no effect on blood pressure in SHRs after a 60-min tMCAO. a Mean arterial pressure (MAP), as measured by telemetry, showed no effect of C21 on BP, in unstroked animals. b There was an increase in MAP from baseline after transient middle cerebral artery occlusion (tMCAO) and this was not affected by C21 administration 2 h after reperfusion, and the average BP trend was similar for both C21 and saline-treated animals. c Figure depicting complete MAP trend, before and after tMCAO, with the effect of treatments administered at different points in time