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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Anti-CD52 antibody treatment depletes B cell aggregates in the central nervous system in a mouse model of multiple sclerosis

Fig. 4

Detection of spinal cord demyelination, axonal damage, and remyelination in MP4-immunized mice. a Luxol Fast Blue staining for the detection of demyelination in spinal cord white matter. b IHC for SMI-32 for the detection of axonal damage in spinal cord white matter. c IHC for Olig2+APC+ oligodendrocytes in spinal cord white matter. Analysis was performed in mice that had received treatment in the chronic stage of EAE. Scale bars denote 100 μm. Graphs show means ± SEM

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