Table 2 Univariate and multivariate linear regression for click hearing threshold in infant rats (n = 29) 4 weeks after surviving an episode of pneumococcal meningitis measured by click stimuli
| Â | Hearing threshold | |||||
|---|---|---|---|---|---|---|
Univariate | Multivariate | |||||
Coef. | 95% CI | p | Coef. | 95% CI | p | |
Log bacterial CSF titre at 18 hpi | 29.5 | 11.13–47.8 | 0.003 | 35.1 | 20.1–50.0 | < 0.001 |
Treatment with combined adjuvant therapy | − 16.8 | − 31.3 to − 2.2 | 0.026 | − 21.7 | − 32.7 to − 10.7 | < 0.001 |
Female sex | 1.8 | − 15.5–19.1 | 0.832 | – | – | – |
Relative weight gain (per add. percent) | − 1.03 | − 2.4–0.4 | 0.141 | – | – | – |
Clinical score at 24 hpi | − 21.7 | − 35.4 to − 7.9 | 0.003 | – | – | – |