Fig. 6
MK-801 treatment reduces lethality in JEV-infected mouse model. Mice were subjected to JEV infection and MK-801 treatment paradigm as described in Fig. 4a. a Survival of mice in each group was monitored for 23 days after JEV inoculation. Data were collected and shown as Kaplan-Meier survival curves. n = 10 mice. b Viral titers in the mouse brain on days 5 and 23 after JEV infection were determined by plaque assay. The viral titers are shown as log10 PFU/ml. n = 5 mice. c Presentation of clinical signs of disease in mice on indicated days following JEV infection. n = 10 mice