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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Netrin-1 attenuates brain injury after middle cerebral artery occlusion via downregulation of astrocyte activation in mice

Fig. 6

NT-1 reduced astrocyte activation and interleukin release after brain ischemia. a GFAP expression in the sham mice, NT-1 protein-injected mice, and the BSA-injected mice 3 days after MCAO. b The statistical results of GFAP expression in the NT-1 and control groups; ***p < 0.001. c The immunofluorescence results of GFAP staining in the peri-infarct area in the NT-1 and control groups; bar = 50 μm, n = 3 in each group. d ELISA results of the expression of chemokines IL-1β and IL-12β in the NT-1-injected mice and the control mice after ischemic stroke. The left graph indicates the IL-1β expression; the right graph indicates the IL-12β expression; *p < 0.05, n = 3–5 in each group

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Journal of Neuroinflammation

ISSN: 1742-2094