Fig. 3From: A comparison of brain magnetic resonance imaging lesions in multiple sclerosis by race with reference to disability progressionRelationship between disease duration and brain volumes in MS. Scatter plots show the relationship between disease duration and brain volumes (NBV, NCGMV, NDGMV, normalized thalamic volume, or NWMV; a–e) in Japanese (black dots) and Caucasian patients (gray dots). The solid lines represent the linear regression of the data. A test of homogeneity of slopes shows significant differences in NDGMV and normalized thalamic volume between the groups (p = 0.001 for both), and a statistically different trend in NBV between the groups (p = 0.06). A test of homogeneity of intercept demonstrated that NBV, NWMV, NDGMV, and normalized thalamic volume were consistently smaller in Japanese versus Caucasian patients throughout the entire disease duration examined (p = 0.046, p = 0.005, p = 0.01, and p = 0.04, respectively), while NCGMV was similar between the two racial groups in the early course of the disease. R2 = coefficient of determinationBack to article page