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Table 1 Comparison of baseline characteristics between Japanese and Caucasian patients with MS

From: A comparison of brain magnetic resonance imaging lesions in multiple sclerosis by race with reference to disability progression

 

Entire study population

Population for T2W-lesion evaluation

Japanese patients (n = 95)

Caucasian patients (n = 246)

p

Japanese patients (n = 93)

Caucasian patients (n = 72)

p

Female (%)

65 (68.4)

179 (72.8)

0.43

65 (69.9)

48 (66.7)

0.74

Age at time of the MRI, yearsa

34.2 ± 8.3

36.9 ± 9.5

0.03

34.0 ± 8.3

35.9 ± 9.8

0.24

Age at first symptom, yearsa

26.9 ± 8.9

29.0 ± 8.5

0.03

26.6 ± 8.7

28.3 ± 8.6

0.15

Duration of disease from first symptom, yearsa

7.4 ± 6.4

7.9 ± 7.2

0.60

7.4 ± 6.4

7.7 ± 8.1

0.75

EDSS scoresa

2.0 ± 1.7

2.3 ± 1.2

0.008

1.9 ± 1.7

2.2 ± 1.3

0.10

MSSSa

3.24 ± 2.61

3.84 ± 2.09

0.01

3.19 ± 2.60

3.78 ± 1.92

0.04

Previous exposure of DMDs or immunosuppressive therapy, n (%)

54 (56.8)

70 (28.5)

< 0.0001

53 (57.0)

22 (30.6)

0.0009

Patients with contrast-enhanced lesions, n (%)

53 (55.8)

126 (51.2)

0.47

52 (55.9)

40 (55.6)

1.00

  1. aValues are expressed as mean ± standard deviation
  2. DMDs Disease modifying drugs, EDSS Kurtzke’s Expanded Disability Status Scale, MS multiple sclerosis, MSSS Multiple Sclerosis Severity Score, T2W T2-weighted