| Entire study population | Population for T2W-lesion evaluation | ||||
---|---|---|---|---|---|---|
Japanese patients (n = 95) | Caucasian patients (n = 246) | p | Japanese patients (n = 93) | Caucasian patients (n = 72) | p | |
Female (%) | 65 (68.4) | 179 (72.8) | 0.43 | 65 (69.9) | 48 (66.7) | 0.74 |
Age at time of the MRI, yearsa | 34.2 ± 8.3 | 36.9 ± 9.5 | 0.03 | 34.0 ± 8.3 | 35.9 ± 9.8 | 0.24 |
Age at first symptom, yearsa | 26.9 ± 8.9 | 29.0 ± 8.5 | 0.03 | 26.6 ± 8.7 | 28.3 ± 8.6 | 0.15 |
Duration of disease from first symptom, yearsa | 7.4 ± 6.4 | 7.9 ± 7.2 | 0.60 | 7.4 ± 6.4 | 7.7 ± 8.1 | 0.75 |
EDSS scoresa | 2.0 ± 1.7 | 2.3 ± 1.2 | 0.008 | 1.9 ± 1.7 | 2.2 ± 1.3 | 0.10 |
MSSSa | 3.24 ± 2.61 | 3.84 ± 2.09 | 0.01 | 3.19 ± 2.60 | 3.78 ± 1.92 | 0.04 |
Previous exposure of DMDs or immunosuppressive therapy, n (%) | 54 (56.8) | 70 (28.5) | < 0.0001 | 53 (57.0) | 22 (30.6) | 0.0009 |
Patients with contrast-enhanced lesions, n (%) | 53 (55.8) | 126 (51.2) | 0.47 | 52 (55.9) | 40 (55.6) | 1.00 |