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Table 1 Comparison of baseline characteristics between Japanese and Caucasian patients with MS

From: A comparison of brain magnetic resonance imaging lesions in multiple sclerosis by race with reference to disability progression

  Entire study population Population for T2W-lesion evaluation
Japanese patients (n = 95) Caucasian patients (n = 246) p Japanese patients (n = 93) Caucasian patients (n = 72) p
Female (%) 65 (68.4) 179 (72.8) 0.43 65 (69.9) 48 (66.7) 0.74
Age at time of the MRI, yearsa 34.2 ± 8.3 36.9 ± 9.5 0.03 34.0 ± 8.3 35.9 ± 9.8 0.24
Age at first symptom, yearsa 26.9 ± 8.9 29.0 ± 8.5 0.03 26.6 ± 8.7 28.3 ± 8.6 0.15
Duration of disease from first symptom, yearsa 7.4 ± 6.4 7.9 ± 7.2 0.60 7.4 ± 6.4 7.7 ± 8.1 0.75
EDSS scoresa 2.0 ± 1.7 2.3 ± 1.2 0.008 1.9 ± 1.7 2.2 ± 1.3 0.10
MSSSa 3.24 ± 2.61 3.84 ± 2.09 0.01 3.19 ± 2.60 3.78 ± 1.92 0.04
Previous exposure of DMDs or immunosuppressive therapy, n (%) 54 (56.8) 70 (28.5) < 0.0001 53 (57.0) 22 (30.6) 0.0009
Patients with contrast-enhanced lesions, n (%) 53 (55.8) 126 (51.2) 0.47 52 (55.9) 40 (55.6) 1.00
  1. aValues are expressed as mean ± standard deviation
  2. DMDs Disease modifying drugs, EDSS Kurtzke’s Expanded Disability Status Scale, MS multiple sclerosis, MSSS Multiple Sclerosis Severity Score, T2W T2-weighted