Fig. 2

Meta-analysis for rs28469012 (CPXM2), rs10894768 (IGSF9B), and rs10423927 (NLRP9) in the two validation cohorts of patients with aggressive and benign disease courses. The figure depicts joint analyses for the first and second validation cohorts in each SNP, with homogeneity tests (I²) and tests for overall effects. The squares and horizontal lines correspond to the study specific odds ratios (ORs) and 95% confidence intervals (CI) respectively. The area of the squares reflects the study specific weight (inverse of the variance). The diamond represents the pooled ORs and 95% CI. M-H Mantel-Haenszel