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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Exome sequencing study in patients with multiple sclerosis reveals variants associated with disease course

Fig. 3

IGSF9B, CPXM2, and NLRP9 expression in MS brain tissue. Immunostainings for IGSF9B, CPXM2, and NLRP9 in the margins of MS brain chronic active lesions, where inflammatory activity is highest. IGSF9B expression was observed in astrocytes (arrows) and macrophages/microglia (arrow heads), whereas CPMX2 and NLRP9 immunostaining was only detected in macrophages/microglia (arrow heads). Photos were taken at × 20 and × 40

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