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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Sphingosine 1-phosphate receptor subtype 3 (S1P3) contributes to brain injury after transient focal cerebral ischemia via modulating microglial activation and their M1 polarization

Fig. 9

CAY10444 (CAY) administration alters tMCAO-induced Akt and MAPK expression in post-ischemic brain. Mice were challenged with tMCAO, and CAY (0.5 mg/kg) was administered intraperitoneally immediately after reperfusion. The effect of CAY on expression in MAPKs and Akt was determined by Western blot analysis. a Representative Western blots. b Quantification. n = 4 mice per group. *p < 0.05, **p < 0.01, and ***p < 0.001 versus sham group, and #p < 0.05 vehicle-treated tMCAO (tMCAO+veh)

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Journal of Neuroinflammation

ISSN: 1742-2094