Disease/model | Reference |
---|---|
Reduced regulation of IL-6 production in aged mice | [211] |
Reversed effects and decreased production of IL-4 and IL-6 in antigen induced immunosuppression in mice | [212] |
Reduced production of IL-6 in splenocytes of retrovirus infected mice as well as aged-induced immunocompromised mice | [213] |
Decreased production of IL-4 and increased production of IL-2 by concanavalin-A-stimulated PBMCs from patients with atopic dermatitis | [214] |
Reduction of TNF-α serum concentrations in obese Zucker rat model | [215] |
Inhibition of IL-6 production in isolated primary human peripheral blood mononuclear cells (PBMCs) | [10] |
Reduced production of IL-1, IL-6 and TNF-α in LPS-stimulated murine macrophage cell line | [216] |
Inhibition of TNF-α-induced nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)-mediated gene transcription in HuH7 human hepatocyte cell line | [217] |
Suppression of pro-inflammatory genes (IL-1β, IL-6, TNF-α) in primary human HIV-positive macrophages, as well as feline immunodeficiency virus (FIV)-positive felines | [218] |
Inhibits acute LPS-induced microglia-mediated inflammation both in vivo and in vitro through the activation of TrkA-Akt1/2-CREB-Jmjd3 pathway and reduces IL-6, TNF-α, IL-12 and MCP-1 gene expression | [64] |