Skip to main content

Table 1 Demographic and baseline clinical characteristics of the MS patients and healthy controls

From: Circulating EZH2-positive T cells are decreased in multiple sclerosis patients

Baseline characteristics

HC

RRMS

SPMS

PPMS

Relapse

Initial cohort

     

N

24

20

20

17

5

 Age (years)

30.2 (7.2)

30.0 (7.8)

45.7 (8.7)

50.2 (7.3)

30.8 (8.7)

 Female/male (% women)

18/6 (75.0)

10/10 (50.0)

11/9 (55.0)

11/6 (64.7)

2/3 (40.0)

 Duration of disease (years)

4.8 (4.6)

11.5 (7.6)

12.2 (7.9)

2.2 (2.7)

 EDSSa

1.7 (1.0–4.2)

4.0 (3.5–5.1)

6.0 (4.0–6.0)

3.0 (2.5–5.3)

 Numbers of relapsesb

2.2 (0.7)

0.8 (0.8)

2.6 (1.3)

Validation cohort

     

N

12

13

   

 Age (years)

28.2 (6.0)

37.6 (9.3)

   

 Female/male (% women)

8/3 (72.7)

12/2 (85.7)

   

 Duration of disease (years)

3.8 (3.2)

   

 EDSSa

2.5 (1.0–3.5)

   

 Numbers of relapsesb

2.5 (0.8)

   
  1. Data are expressed as mean (standard deviation) unless otherwise stated
  2. RRMS relapsing-remitting multiple sclerosis, SPMS secondary progressive multiple sclerosis, PPMS primary progressive multiple sclerosis, Relapse RRMS patients whose blood was collected at the time of an acute exacerbation
  3. aData are expressed as mean (interquartile range)
  4. bThe number of relapses in the 2 years before blood collection