Fig. 3
From: Protein kinase C-delta inhibition protects blood-brain barrier from sepsis-induced vascular damage
Cytokine-induced PKCδ phosphorylation in vitro is attenuated by PKCδ inhibition. a Representative immunostaining images of phosphor-PKCδ distribution in non-treated, TNF-α-activated, or TNF-α + PKCδ-i-treated HBMVEC in static culture. b Fluorescence intensity analysis of phosphorylated PKCδ (Ser643) translocation. Values are expressed as the intensity ratio of the cell nucleus to the cytosol. Data are presented as mean ± SEM (n = 3). ***p < 0.0001 compared to no treatment and TNF-α + PKCδ-i by ANOVA with Tukey-Kramer post hoc