Fig. 10

STING^−/− brains exhibit ramified microglial flux 24 h post-TBI. a LC3, (c) p62 and (e) LAMP2 expression was detected in wild-type and STING^−/− brains (n = 6) by Western blot. LC3-I, LC3-II, p62 and LAMP2 levels were normalised to β-actin levels respectively. For densitometry calculations, b LC3-II/LC3-I ratio, d p62/β-actin ratio and f LAMP2/β-actin ratio was then determined from these values and was calculated as a fold change relative to genotype sham control. Data is expressed as mean ± SEM, **p < 0.01; ***p < 0.001. IC ipsilateral cortex, IS ipsilateral striatum