Fig. 5

STING^−/− mice display reduced type-I IFN signalling after TBI. QPCR analysis identified increased mRNA expression of IRF3 (a), IRF7 (b), IFNα (c) and IFN-β (d) in WT brains mice as compared to STING^−/− mice after CCI (n = 6). Data represents mean ± SEM, *p < 0.05; ***p < 0.0001. IC ipsilateral cortex, IS ipsilateral striatum, CC contralateral cortex, CS contralateral striatum