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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury

Fig. 7

STING−/− mice display reduced GFAP protein expression following TBI. a Representative images (n = 6 mice for each genotype and timepoint) showing GFAP protein levels in wild-type and STING−/− mice after TBI as assessed by western blot analysis. Significantly increased expression of GFAP was observed in the ipsilateral striatum of wild-type mice 24 h post-TBI but not in STING−/− mice as compared with sham group, as quantified in (b). Data represent mean ± SEM, *p < 0.05. IC ipsilateral cortex, IS ipsilateral striatum, CC contralateral cortex, CS contralateral striatum

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